Genealogical Estimation of Variant Age (GEVA)
Inference of the ancestral origin of a genetic variant at a single locus
Unmatched Variant ID, using internal ID instead:
X436632766
Alleles:
reference
T–
alternate
C–
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
Chromosome
2
position 136,632,766 (GRCh37)
Allele frequency in SGDP ⇪
| Sample | 99.6% |
0.4% |
|
AFR |
97.7% |
2.3% |
|
AMR |
100.0% |
0.0% |
|
CAS |
100.0% |
0.0% |
|
EAS |
100.0% |
0.0% |
|
OCN |
100.0% |
0.0% |
|
SAS |
100.0% |
0.0% |
|
WEA |
100.0% |
0.0% |
|
| reference | ← allele frequency → | alternate |
Select clock model
Age estimation summary
| Data source | Estimated age of C allele |
# pairs = concordant + discordant | Quality score |
|---|---|---|---|
| Genomes in SGDP | 952.1 generations | 97 = 1 + 96 | 1.000 |
Pairwise results table
| Haplotype pair | Pair type | Data source | Breakpoint positions | Physical length (bp) | Genetic Length (cM) | α | β | Mean TMRCA (generations) |
|---|---|---|---|---|---|---|---|---|
| S_Khomani_San-2A + S_Khomani_San-2B | Concordant | SGDP | 135,755,745 – 136,781,557 |
1,025,812.0 |
0.16248506 |
18 | 493.3898 | 729.6 |
| S_Khomani_San-2B + S_Mansi-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Kinh-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Hezhen-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Pima-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_North_Ossetian-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Samaritan-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Estonian-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Naxi-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Cambodian-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Mansi-1A | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
18 | 83.7304 | 4,299.5 |
| S_Khomani_San-2A + S_Eskimo_Sireniki-1A | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
14 | 77.9634 | 3,591.4 |
| S_Khomani_San-2A + S_Mixtec-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Mixe-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Punjabi-3B | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
11 | 83.7304 | 2,627.5 |
| S_Khomani_San-2B + S_Czech-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Miao-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Saami-2B | Discordant | SGDP | 136,563,445 – 136,762,052 |
198,607.0 |
0.02158089 |
16 | 96.3314 | 3,321.9 |
| S_Khomani_San-2A + S_Oroqen-1B | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
15 | 77.9634 | 3,848.0 |
| S_Khomani_San-2B + S_Orcadian-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Oroqen-2B | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
16 | 77.9634 | 4,104.5 |
| S_Khomani_San-2B + B_Karitiana-3A | Discordant | SGDP | 136,590,087 – 136,735,800 |
145,712.5 |
0.01681350 |
12 | 70.9420 | 3,383.0 |
| S_Khomani_San-2A + S_Xibo-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Aleut-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Dusun-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Yi-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Itelman-1A | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
15 | 77.9634 | 3,848.0 |
| S_Khomani_San-2B + S_Eskimo_Naukan-2A | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
11 | 77.9634 | 2,821.8 |
| S_Khomani_San-2A + S_Madiga-1A | Discordant | SGDP | 136,619,416 – 136,762,052 |
142,636.0 |
0.01397324 |
13 | 69.4653 | 3,742.9 |
| S_Khomani_San-2B + S_Somali-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Brahmin-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Abkhasian-1B | Discordant | SGDP | 136,568,364 – 136,735,800 |
167,436.0 |
0.02019511 |
10 | 81.3693 | 2,457.9 |
| S_Khomani_San-2A + S_Burusho-1A | Discordant | SGDP | 136,619,416 – 136,762,052 |
142,636.0 |
0.01397324 |
14 | 69.4653 | 4,030.8 |
| S_Khomani_San-2B + S_English-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Sindhi-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Finnish-1B | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
12 | 83.7304 | 2,866.3 |
| S_Khomani_San-2A + S_Punjabi-2A | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
18 | 83.7304 | 4,299.5 |
| S_Khomani_San-2B + S_Icelandic-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Bulgarian-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Sardinian-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Bulgarian-1B | Discordant | SGDP | 136,563,445 – 136,714,614 |
151,169.0 |
0.02015013 |
13 | 73.5611 | 3,534.5 |
| S_Khomani_San-2B + S_Polish-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Atayal-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_North_Ossetian-2B | Discordant | SGDP | 136,568,364 – 136,642,220 |
73,856.5 |
0.01276542 |
4 | 36.4511 | 2,194.7 |
| S_Khomani_San-2A + S_BantuKenya-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Piapoco-1B | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
11 | 83.7304 | 2,627.5 |
| S_Khomani_San-2A + S_Finnish-3A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Mozabite-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Saami-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Dai-3B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_French-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Uygur-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_French-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Xibo-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Hungarian-2A | Discordant | SGDP | 136,602,042 – 136,762,052 |
160,010.0 |
0.01668088 |
14 | 77.8048 | 3,598.7 |
| S_Khomani_San-2B + S_Chukchi-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Iranian-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Mozabite-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Tuscan-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Kapu-1A | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
13 | 83.7304 | 3,105.2 |
| S_Khomani_San-2A + S_Jordanian-3A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Burusho-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Kyrgyz-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Punjabi-4A | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
12 | 83.7304 | 2,866.3 |
| S_Khomani_San-2A + S_Adygei-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Bulgarian-2A | Discordant | SGDP | 136,563,445 – 136,711,848 |
148,403.0 |
0.02012122 |
10 | 72.2334 | 2,768.8 |
| S_Khomani_San-2A + S_Spanish-1B | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
15 | 83.7304 | 3,582.9 |
| S_Khomani_San-2B + S_English-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Spanish-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Estonian-2A | Discordant | SGDP | 136,563,445 – 136,677,400 |
113,955.5 |
0.01928611 |
8 | 55.6986 | 2,872.6 |
| S_Khomani_San-2A + S_Tajik-2A | Discordant | SGDP | 136,619,416 – 136,735,800 |
116,384.0 |
0.01275843 |
8 | 56.8643 | 2,813.7 |
| S_Khomani_San-2B + S_Estonian-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Yemenite_Jew-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Finnish-3A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Yemenite_Jew-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Basque-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Yemenite_Jew-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Icelandic-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + B_Crete-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Palestinian-1A | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
8 | 83.7304 | 1,910.9 |
| S_Khomani_San-2A + B_Sardinian-3B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Norwegian-1A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Chane-1A | Discordant | SGDP | 136,563,445 – 136,735,800 |
172,355.0 |
0.02036609 |
16 | 83.7304 | 3,821.8 |
| S_Khomani_San-2B + S_Orcadian-2A | Discordant | SGDP | 136,563,445 – 136,762,052 |
198,607.0 |
0.02158089 |
14 | 96.3314 | 2,906.6 |
| S_Khomani_San-2A + S_Piapoco-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Lezgin-2B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2A + S_Pima-1A | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
14 | 77.9634 | 3,591.4 |
| S_Khomani_San-2B + S_North_Ossetian-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Mongola-2A | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Turkish-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Tubalar-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
| S_Khomani_San-2B + S_Saharawi-2A | Discordant | SGDP | 136,563,445 – 136,678,814 |
115,369.5 |
0.01948962 |
10 | 56.3774 | 3,547.5 |
| S_Khomani_San-2B + S_Even-2B | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
11 | 77.9634 | 2,821.8 |
| S_Khomani_San-2B + S_Pima-1A | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
11 | 77.9634 | 2,821.8 |
| S_Khomani_San-2B + S_Eskimo_Chaplin-1A | Discordant | SGDP | 136,563,445 – 136,762,052 |
198,607.0 |
0.02158089 |
16 | 96.3314 | 3,321.9 |
| S_Khomani_San-2B + S_Pima-2B | Discordant | SGDP | 136,590,087 – 136,750,428 |
160,340.5 |
0.01697273 |
12 | 77.9634 | 3,078.4 |
| S_Khomani_San-2B + S_Tlingit-1B | Discordant | SGDP | 136,632,738 – 136,632,796 |
57.5 |
0.00001479 |
2 | 1.0276 | 38,925.7 |
Data shown in this table can be downloaded from this page.
| α | Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| β | Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| Mean TMRCA | Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default. |
|---|
Patrick K. Albers