HumanGenomeDating
Atlas of Variant Age
Search
Examples: LCT, MCM6, EDAR, ZEB1
Shared Ancestry Database
TGP
1000 Genomes Project
Populations: 26
Individuals: 2,535
Ancestry analyses:565,507,800
Watch movie
SGDP
Simons Genome Diversity Project
Populations: 130
Individuals: 278
Ancestry analyses:6,800,992
Watch movie
Shared Ancestry Movies
About
Bulk downloads
Frequently Asked Questions
Citation
Download profile data
for this variant in csv format

Genealogical Estimation of Variant Age (GEVA)

Inference of the ancestral origin of a genetic variant at a single locus

rs373267093
Alleles:
reference
G
ancestral
alternate
A
derived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome 2   position  136,585,219  (GRCh37) Explore rs373267093 on Ensembl!
Allele frequency in   SGDP ⇪
Sample 98.9%
1.1%
AFR 100.0%
0.0%
AMR 100.0%
0.0%
CAS 100.0%
0.0%
EAS 100.0%
0.0%
OCN 88.0%
12.0%
SAS 100.0%
0.0%
WEA 100.0%
0.0%
reference ← allele frequency → alternate
Select clock model
  Mutation clock
  Recombination clock
  Joint clock
Age estimation summary Joint clock
Data source Estimated age of A allele # pairs = concordant + discordant Quality score
    Genomes in SGDP677.2 generations 105  =  11  +  940.818
Pairwise results table Joint clock
Haplotype pair Pair type Data source Breakpoint positions Physical length (bp) Genetic Length (cM) α β Mean TMRCA (generations)
S_Papuan-5B + S_Papuan-12B Concordant SGDP 135,758,336 – 136,646,325 887,989.0 0.09856159 7 506.0840 276.6
S_Papuan-5A + S_Papuan-4A Concordant SGDP 135,758,336 – 136,762,052 1,003,716.0 0.10634626 27 567.8607 950.9
S_Papuan-5B + S_Papuan-5A Concordant SGDP 135,758,336 – 136,646,325 887,989.0 0.09856159 23 506.0840 908.9
S_Papuan-6A + S_Papuan-4A Concordant SGDP 135,758,336 – 136,762,052 1,003,716.0 0.10634626 18 567.8607 634.0
S_Papuan-6A + S_Papuan-12B Concordant SGDP 135,758,336 – 136,788,485 1,030,149.5 0.15304406 14 617.9070 453.1
S_Papuan-6A + S_Papuan-5B Concordant SGDP 135,758,336 – 136,646,325 887,989.0 0.09856159 14 506.0840 553.3
S_Papuan-3A + S_Papuan-12B Concordant SGDP 135,757,046 – 136,976,448 1,219,402.0 0.36788382 27 880.6200 613.2
S_Papuan-3A + S_Papuan-4A Concordant SGDP 135,282,355 – 136,762,052 1,479,697.0 0.49506966 22 1,107.3103 397.4
S_Papuan-4A + S_Papuan-12B Concordant SGDP 135,758,336 – 136,762,052 1,003,716.0 0.10634626 11 567.8607 387.4
S_Papuan-3A + S_Papuan-5B Concordant SGDP 135,339,363 – 136,631,099 1,291,736.0 0.38765847 17 931.1601 365.1
S_Papuan-3A + S_Papuan-6A Concordant SGDP 135,758,336 – 136,789,046 1,030,710.0 0.16203451 16 625.3684 511.7
S_Papuan-4A + S_Estonian-2A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Chukchi-1A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 21 159.8383 2,627.7
S_Papuan-4A + S_Punjabi-2B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 23 159.8383 2,877.9
S_Papuan-4A + S_Mozabite-2A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 26 159.8383 3,253.3
S_Papuan-4A + S_Ami-2A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Kyrgyz-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Saharawi-2A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-3A + S_Adygei-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-3A + S_Surui-1B Discordant SGDP 135,340,792 – 136,785,841 1,445,048.5 0.39496084 61 1,010.5920 1,207.2
S_Papuan-3A + S_Papuan-2B Discordant SGDP 135,760,098 – 137,032,475 1,272,377.0 0.42798512 86 954.1291 1,802.7
S_Papuan-3A + S_Mala-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-3A + S_Thai-2B Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 20 182.9998 2,185.8
S_Papuan-3A + S_Cambodian-2A Discordant SGDP 135,760,098 – 136,785,841 1,025,743.0 0.10319507 34 575.9127 1,180.7
S_Papuan-3A + S_Tubalar-2B Discordant SGDP 135,760,098 – 136,976,283 1,216,185.5 0.31932188 90 840.2265 2,142.3
S_Papuan-4A + S_Saami-1A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-3A + S_Karitiana-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Icelandic-1A Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-6A + S_Even-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Adygei-2A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-6A + S_Yi-1B Discordant SGDP 135,760,098 – 136,762,052 1,001,954.0 0.08851659 37 552.7512 1,338.8
S_Papuan-3A + S_Zapotec-2A Discordant SGDP 136,489,176 – 136,976,283 487,107.0 0.26562788 71 447.3137 3,174.5
S_Papuan-6A + S_Tujia-1A Discordant SGDP 135,760,098 – 136,784,585 1,024,487.5 0.10077474 35 573.3738 1,220.8
S_Papuan-4A + S_Dai-1B Discordant SGDP 135,978,431 – 136,631,099 652,668.0 0.06199239 28 363.8746 1,539.0
S_Papuan-6A + S_Eskimo_Sireniki-2B Discordant SGDP 135,760,098 – 136,785,841 1,025,743.0 0.10319507 42 575.9127 1,458.6
S_Papuan-4A + S_Dusun-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-6A + B_Crete-2A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 11 159.8383 1,376.4
S_Papuan-4A + S_Khonda_Dora-1A Discordant SGDP 135,340,792 – 136,762,052 1,421,259.5 0.38028236 60 987.4305 1,215.3
S_Papuan-5B + S_Lezgin-2B Discordant SGDP 136,489,176 – 136,646,325 157,148.5 0.02703793 7 98.0616 1,427.7
S_Papuan-4A + S_English-1A Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-5B + S_Piapoco-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Finnish-3A Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-4A + S_Mozabite-1B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 24 159.8383 3,003.0
S_Papuan-4A + S_French-2A Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 11 88.6720 2,481.1
S_Papuan-4A + S_Even-3A Discordant SGDP 135,760,098 – 136,762,052 1,001,954.0 0.08851659 46 552.7512 1,664.4
S_Papuan-4A + S_Iranian-1B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 21 159.8383 2,627.7
S_Papuan-4A + S_Aleut-2A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Orcadian-2B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 22 159.8383 2,752.8
S_Papuan-4A + S_Oroqen-1B Discordant SGDP 136,489,176 – 136,590,087 100,911.0 0.01679429 8 62.8727 2,544.8
S_Papuan-4A + S_Yemenite_Jew-2A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 21 159.8383 2,627.7
S_Papuan-4A + S_Xibo-1B Discordant SGDP 135,978,431 – 136,631,099 652,668.0 0.06199239 33 363.8746 1,813.8
S_Papuan-5A + S_Tubalar-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-3A + S_Zapotec-1A Discordant SGDP 136,489,176 – 137,032,475 543,298.5 0.37429113 71 561.2162 2,530.2
S_Papuan-5B + B_Sardinian-3A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5A + S_Naxi-2A Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 19 182.9998 2,076.5
S_Papuan-5B + S_Pima-2A Discordant SGDP 136,489,176 – 136,642,620 153,443.5 0.02626792 10 95.6672 2,090.6
S_Papuan-5A + S_Tujia-1B Discordant SGDP 135,760,098 – 136,785,841 1,025,743.0 0.10319507 56 575.9127 1,944.7
S_Papuan-4A + S_Mongola-2A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 20 159.8383 2,502.5
S_Papuan-5A + S_Xibo-2B Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 12 182.9998 1,311.5
S_Papuan-4A + S_Tlingit-1A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 23 159.8383 2,877.9
S_Papuan-5A + S_Mansi-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Miao-2B Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 12 88.6720 2,706.6
S_Papuan-5A + S_Sindhi-2B Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 15 182.9998 1,639.3
S_Papuan-4A + S_Xibo-1A Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 20 159.8383 2,502.5
S_Papuan-5A + S_Atayal-1B Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 11 182.9998 1,202.2
S_Papuan-4A + S_Yi-2B Discordant SGDP 136,489,176 – 136,590,087 100,911.0 0.01679429 7 62.8727 2,226.7
S_Papuan-5A + S_English-2B Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 12 182.9998 1,311.5
S_Papuan-4A + S_Uygur-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5A + S_Estonian-1A Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 12 182.9998 1,311.5
S_Papuan-4A + S_Burmese-2A Discordant SGDP 135,760,098 – 136,762,052 1,001,954.0 0.08851659 51 552.7512 1,845.3
S_Papuan-5A + S_Basque-1A Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 12 182.9998 1,311.5
S_Papuan-4A + S_Kinh-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5A + S_Norwegian-1B Discordant SGDP 136,489,176 – 136,785,841 296,664.5 0.04950107 13 182.9998 1,420.8
S_Papuan-4A + S_Papuan-13A Discordant SGDP 135,343,836 – 137,188,964 1,845,128.0 1.07760872 85 1,748.7484 972.1
S_Papuan-5A + S_Spanish-2B Discordant SGDP 136,493,766 – 136,762,052 268,286.0 0.03370694 13 156.7428 1,658.8
S_Papuan-4A + S_Eskimo_Naukan-1A Discordant SGDP 135,340,792 – 136,631,099 1,290,307.0 0.36989600 46 916.2642 1,004.1
S_Papuan-5A + S_Yemenite_Jew-1B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 11 159.8383 1,376.4
S_Papuan-4A + S_Brahmin-2B Discordant SGDP 136,493,766 – 136,762,052 268,286.0 0.03370694 21 156.7428 2,679.5
S_Papuan-5A + S_Pima-1A Discordant SGDP 136,489,176 – 136,585,227 96,050.5 0.01506635 7 59.1573 2,366.6
S_Papuan-4A + S_Bulgarian-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5B + S_Mixtec-2A Discordant SGDP 136,489,176 – 136,642,620 153,443.5 0.02626792 8 95.6672 1,672.5
S_Papuan-4A + S_English-2A Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-5B + S_Altaian-1B Discordant SGDP 135,760,098 – 136,646,325 886,227.0 0.08073192 24 490.9745 977.6
S_Papuan-4A + S_Finnish-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5B + S_Cambodian-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_BantuKenya-1B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 23 159.8383 2,877.9
S_Papuan-5B + S_Cambodian-2A Discordant SGDP 135,760,098 – 136,646,325 886,227.0 0.08073192 17 490.9745 692.5
S_Papuan-4A + S_Saami-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5B + S_Naxi-3A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Basque-1B Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-5B + S_Uygur-1A Discordant SGDP 136,489,176 – 136,646,325 157,148.5 0.02703793 8 98.0616 1,631.6
S_Papuan-4A + S_Icelandic-1B Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-5B + S_Xibo-2A Discordant SGDP 135,760,098 – 136,642,620 882,522.0 0.07996192 28 488.5801 1,146.2
S_Papuan-4A + S_Tuscan-2B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 21 159.8383 2,627.7
S_Papuan-5B + S_Japanese-1A Discordant SGDP 135,760,398 – 136,646,325 885,927.0 0.08009265 21 490.3191 856.6
S_Papuan-4A + S_Orcadian-1A Discordant SGDP 136,489,176 – 136,631,099 141,923.0 0.02443623 10 88.6720 2,255.5
S_Papuan-5B + S_Dusun-2B Discordant SGDP 136,489,176 – 136,642,620 153,443.5 0.02626792 12 95.6672 2,508.7
S_Papuan-4A + S_North_Ossetian-1B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 24 159.8383 3,003.0
S_Papuan-5B + S_Burusho-2B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-4A + S_Turkish-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-5B + S_French-2B Discordant SGDP 136,489,176 – 136,646,325 157,148.5 0.02703793 6 98.0616 1,223.7
S_Papuan-4A + S_Yemenite_Jew-1B Discordant SGDP 136,489,176 – 136,762,052 272,875.5 0.03482260 22 159.8383 2,752.8
S_Papuan-5B + S_Samaritan-1B Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
S_Papuan-12B + S_Yadava-2A Discordant SGDP 135,760,098 – 136,976,283 1,216,185.5 0.31932188 44 840.2265 1,047.3
S_Papuan-5B + S_Kyrgyz-1A Discordant SGDP 136,585,210 – 136,585,227 17.0 0.00000849 4 1.0150 78,821.5
View as figure
Data shown in this table can be downloaded from this page.
α Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
β Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
Mean TMRCA Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default.
 

The human.genome.dating database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of human.genome.dating are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

human.genome.dating © 2019 - 2025 Contact Terms & Conditions This website does not use cookies and does not collect any personal information about you.