HumanGenomeDating
Atlas of Variant Age
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Examples: LCT, MCM6, EDAR, ZEB1
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TGP
1000 Genomes Project
Populations: 26
Individuals: 2,535
Ancestry analyses:565,507,800
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SGDP
Simons Genome Diversity Project
Populations: 130
Individuals: 278
Ancestry analyses:6,800,992
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Genealogical Estimation of Variant Age (GEVA)

Inference of the ancestral origin of a genetic variant at a single locus

rs567747797
Alleles:
reference
C
ancestral
alternate
A
derived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome 10   position  31,684,601  (GRCh37) Explore rs567747797 on Ensembl!
Allele frequency in   SGDP ⇪
Sample 99.6%
0.4%
AFR 100.0%
0.0%
AMR 100.0%
0.0%
CAS 100.0%
0.0%
EAS 100.0%
0.0%
OCN 100.0%
0.0%
SAS 100.0%
0.0%
WEA 98.7%
1.3%
reference ← allele frequency → alternate
Select clock model
  Mutation clock
  Recombination clock
  Joint clock
Age estimation summary Joint clock
Data source Estimated age of A allele # pairs = concordant + discordant Quality score
    Genomes in SGDP612.3 generations 94  =  1  +  931.000
Pairwise results table Joint clock
Haplotype pair Pair type Data source Breakpoint positions Physical length (bp) Genetic Length (cM) α β Mean TMRCA (generations)
S_Druze-1B + S_Yemenite_Jew-2B Concordant SGDP 31,496,096 – 31,979,966 483,870.0 0.27818692 13 455.8071 570.4
S_Druze-1B + S_Abkhasian-1B Discordant SGDP 31,645,663 – 31,684,619 38,956.0 0.00027606 4 19.9197 4,016.1
S_Druze-1B + S_Balochi-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Kusunda-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Mala-3A Discordant SGDP 31,601,307 – 31,868,351 267,044.5 0.01132961 13 138.2450 1,880.7
S_Druze-1B + S_Piapoco-2B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Orcadian-2A Discordant SGDP 31,583,614 – 31,684,619 101,004.5 0.00254291 7 51.5165 2,717.6
S_Druze-1B + S_Iraqi_Jew-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Even-3A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Ulchi-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Ulchi-2B Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 7 42.4313 3,299.4
S_Druze-1B + S_Tubalar-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Altaian-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Tubalar-2B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 13 147.3302 1,764.7
S_Druze-1B + S_Mongola-2B Discordant SGDP 31,583,614 – 31,751,883 168,269.0 0.00481684 6 85.6226 1,401.5
S_Druze-1B + S_English-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_French-1A Discordant SGDP 31,583,614 – 31,684,619 101,004.5 0.00254291 7 51.5165 2,717.6
S_Druze-1B + S_Even-2B Discordant SGDP 31,134,695 – 31,792,748 658,052.5 0.24443426 46 512.4126 1,795.4
S_Druze-1B + S_Sardinian-1A Discordant SGDP 31,040,456 – 31,684,619 644,163.0 0.36731503 24 604.0503 794.6
S_Druze-1B + S_Yakut-2B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + B_French-3A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Even-1B Discordant SGDP 31,645,663 – 31,684,619 38,956.0 0.00027606 4 19.9197 4,016.1
S_Yemenite_Jew-2B + S_Armenian-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Naxi-3B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Madiga-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Miao-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Brahui-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Han-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Kalash-1A Discordant SGDP 31,139,237 – 31,684,619 545,382.0 0.23647496 40 451.9633 1,770.1
S_Druze-1B + S_Tu-2B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 55 457.7692 2,403.0
S_Druze-1B + S_Bulgarian-1A Discordant SGDP 31,134,695 – 31,868,351 733,656.0 0.25053506 32 553.5829 1,156.1
S_Druze-1B + S_Oroqen-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Finnish-2A Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 53 457.7692 2,315.6
S_Druze-1B + S_Uygur-1A Discordant SGDP 31,636,829 – 31,684,619 47,789.5 0.00071251 5 24.5090 4,080.1
S_Druze-1B + S_French-2B Discordant SGDP 31,112,961 – 31,684,619 571,657.5 0.27702690 44 497.0171 1,770.6
S_Druze-1B + S_Yi-2A Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 6 42.4313 2,828.1
S_Druze-1B + S_Palestinian-3A Discordant SGDP 31,134,695 – 31,868,351 733,656.0 0.25053506 35 553.5829 1,264.5
S_Druze-1B + S_Dai-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Jordanian-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Uygur-2A Discordant SGDP 31,134,695 – 31,727,319 592,624.0 0.24244048 51 479.4119 2,127.6
S_Druze-1B + S_Adygei-2A Discordant SGDP 31,583,614 – 31,792,748 209,133.5 0.00596976 9 106.1599 1,695.6
S_Druze-1B + S_She-2A Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 44 457.7692 1,922.4
S_Druze-1B + S_Chane-1B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 49 457.7692 2,140.8
S_Druze-1B + S_Korean-2B Discordant SGDP 31,684,600 – 31,792,748 108,148.0 0.00342691 7 55.6526 2,515.6
S_Druze-1B + S_Mayan-1A Discordant SGDP 31,134,695 – 31,792,748 658,052.5 0.24443426 59 512.4126 2,302.8
S_Druze-1B + S_Korean-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Quechua-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Burmese-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Brahmin-1A Discordant SGDP 31,134,695 – 31,841,841 707,146.0 0.24835638 51 539.1152 1,892.0
S_Druze-1B + S_Thai-1A Discordant SGDP 31,583,614 – 31,751,883 168,269.0 0.00481684 8 85.6226 1,868.7
S_Druze-1B + S_Madiga-2B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 16 147.3302 2,172.0
S_Druze-1B + S_Kinh-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Kusunda-2B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Kinh-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Pathan-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + B_Australian-3B Discordant SGDP 31,134,695 – 31,795,978 661,282.5 0.24516534 39 514.5479 1,515.9
S_Druze-1B + S_Burusho-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Dusun-1B Discordant SGDP 31,583,614 – 31,751,883 168,269.0 0.00481684 6 85.6226 1,401.5
S_Druze-1B + S_Punjabi-4B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Maori-1B Discordant SGDP 31,601,307 – 31,755,646 154,339.0 0.00471962 8 78.8584 2,029.0
S_Druze-1B + S_Albanian-1B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Bougainville-2B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 12 147.3302 1,629.0
S_Druze-1B + S_Czech-2A Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 6 42.4313 2,828.1
S_Druze-1B + S_Papuan-3A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Estonian-2B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 39 457.7692 1,703.9
S_Druze-1B + S_Papuan-1B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 11 147.3302 1,493.2
S_Druze-1B + S_Finnish-1A Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 10 147.3302 1,357.5
S_Druze-1B + S_Papuan-5B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_French-1B Discordant SGDP 31,040,456 – 31,684,619 644,163.0 0.36731503 48 604.0503 1,589.3
S_Druze-1B + S_Papuan-4A Discordant SGDP 31,583,614 – 31,795,978 212,363.5 0.00670084 8 108.2952 1,477.4
S_Druze-1B + S_Iraqi_Jew-2B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 60 457.7692 2,621.4
S_Druze-1B + S_Papuan-4B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 13 147.3302 1,764.7
S_Druze-1B + S_Iraqi_Jew-1B Discordant SGDP 31,134,695 – 31,868,351 733,656.0 0.25053506 51 553.5829 1,842.5
S_Druze-1B + S_Papuan-14B Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 6 42.4313 2,828.1
S_Druze-1B + S_Bergamo-2B Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 7 42.4313 3,299.4
S_Druze-1B + S_Papuan-7A Discordant SGDP 31,134,695 – 31,868,351 733,656.0 0.25053506 56 553.5829 2,023.2
S_Druze-1B + S_Tuscan-2B Discordant SGDP 31,583,614 – 31,684,619 101,004.5 0.00254291 7 51.5165 2,717.6
S_Druze-1B + S_Papuan-7B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 11 147.3302 1,493.2
S_Druze-1B + S_Jordanian-1A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Papuan-9A Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 11 147.3302 1,493.2
S_Druze-1B + S_Polish-1A Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 6 42.4313 2,828.1
S_Druze-1B + S_Papuan-12B Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 12 147.3302 1,629.0
S_Druze-1B + B_Dai-4A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Papuan-2A Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + B_Papuan-15A Discordant SGDP 31,601,307 – 31,684,619 83,312.0 0.00180195 6 42.4313 2,828.1
S_Druze-1B + S_Chukchi-1B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 42 457.7692 1,835.0
S_Druze-1B + S_Karitiana-1B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 46 457.7692 2,009.7
S_Druze-1B + S_Itelman-1A Discordant SGDP 31,134,695 – 31,868,351 733,656.0 0.25053506 44 553.5829 1,589.6
S_Druze-1B + S_Pima-2B Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 45 457.7692 1,966.1
S_Druze-1B + S_Mansi-2A Discordant SGDP 31,134,695 – 31,684,619 549,923.5 0.24100741 37 457.7692 1,616.5
S_Yemenite_Jew-2B + S_Kalash-2B Discordant SGDP 31,684,600 – 31,684,619 19.0 0.00000006 4 1.0092 79,273.5
S_Druze-1B + S_Kapu-1B Discordant SGDP 31,134,695 – 31,755,646 620,950.5 0.24392508 41 494.1963 1,659.3
S_Yemenite_Jew-2B + S_Saami-1A Discordant SGDP 31,112,961 – 31,684,619 571,657.5 0.27702690 54 497.0171 2,173.0
S_Druze-1B + S_Irula-1A Discordant SGDP 31,583,614 – 31,868,351 284,737.0 0.01207056 11 147.3302 1,493.2
View as figure
Data shown in this table can be downloaded from this page.
α Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
β Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
Mean TMRCA Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default.
 

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