HumanGenomeDating
Atlas of Variant Age
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Examples: LCT, MCM6, EDAR, ZEB1
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TGP
1000 Genomes Project
Populations: 26
Individuals: 2,535
Ancestry analyses:565,507,800
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SGDP
Simons Genome Diversity Project
Populations: 130
Individuals: 278
Ancestry analyses:6,800,992
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Genealogical Estimation of Variant Age (GEVA)

Inference of the ancestral origin of a genetic variant at a single locus

rs770117710
Alleles:
reference
T
ancestral
alternate
C
derived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome 2   position  136,566,027  (GRCh37) Explore rs770117710 on Ensembl!
Allele frequency in   SGDP ⇪
Sample 99.6%
0.4%
AFR 100.0%
0.0%
AMR 100.0%
0.0%
CAS 100.0%
0.0%
EAS 100.0%
0.0%
OCN 100.0%
0.0%
SAS 100.0%
0.0%
WEA 98.7%
1.3%
reference ← allele frequency → alternate
Select clock model
  Mutation clock
  Recombination clock
  Joint clock
Age estimation summary Mutation clock
Data source Estimated age of C allele # pairs = concordant + discordant Quality score
    Genomes in SGDP441.7 generations 95  =  1  +  940.989
Pairwise results table Mutation clock
Haplotype pair Pair type Data source Breakpoint positions Physical length (bp) Genetic Length (cM) α β Mean TMRCA (generations)
S_Abkhasian-1B + S_North_Ossetian-2B Concordant SGDP 136,389,477 – 136,787,291 397,814.0 0.08369446 5 191.9507 521.0
S_North_Ossetian-2B + S_Czech-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 17 85.6250 3,970.8
S_North_Ossetian-2B + S_Punjabi-3B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 5 42.7979 2,336.6
S_North_Ossetian-2B + S_Burusho-1B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 6 42.7979 2,803.9
S_Abkhasian-1B + S_Mixe-2A Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 29 387.8574 1,495.4
S_North_Ossetian-2B + S_Yemenite_Jew-2B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 5 42.7979 2,336.6
S_North_Ossetian-2B + S_Norwegian-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Basque-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_Abkhasian-1B + S_Oroqen-2B Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 36 387.8574 1,856.4
S_Abkhasian-1B + S_Oroqen-1A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_Abkhasian-1B + S_Mansi-1A Discordant SGDP 135,597,516 – 136,785,841 1,188,325.0 0.26173649 31 571.3960 1,085.1
S_Abkhasian-1B + S_Eskimo_Chaplin-1B Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 29 387.8574 1,495.4
S_Abkhasian-1B + S_Even-2A Discordant SGDP 135,760,098 – 136,762,052 1,001,954.0 0.08851659 35 481.9379 1,452.5
S_Abkhasian-1B + S_Eskimo_Sireniki-1B Discordant SGDP 136,555,141 – 136,762,052 206,910.5 0.02601890 5 100.3170 996.8
S_North_Ossetian-2B + S_Estonian-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Finnish-3B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 17 85.6250 3,970.8
S_Abkhasian-1B + S_Hezhen-1B Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 27 387.8574 1,392.3
S_North_Ossetian-2B + S_Samaritan-1B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_Abkhasian-1B + S_Dai-2B Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 37 387.8574 1,907.9
S_North_Ossetian-2B + S_North_Ossetian-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_Abkhasian-1B + S_Itelman-1A Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 30 387.8574 1,547.0
S_North_Ossetian-2B + S_Saharawi-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_Abkhasian-1B + S_Eskimo_Naukan-2A Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 30 387.8574 1,547.0
S_North_Ossetian-2B + S_Madiga-1B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 7 42.7979 3,271.2
S_Abkhasian-1B + S_Mansi-2B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Sindhi-2A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_Abkhasian-1B + S_Bulgarian-1B Discordant SGDP 136,021,995 – 136,976,283 954,288.0 0.30225436 26 459.0582 1,132.8
S_North_Ossetian-2B + S_Bulgarian-1A Discordant SGDP 136,394,329 – 136,566,051 171,722.0 0.02943990 16 83.4266 3,835.7
S_Abkhasian-1B + S_Bulgarian-2A Discordant SGDP 135,760,098 – 136,785,841 1,025,743.0 0.10319507 14 493.3566 567.5
S_North_Ossetian-2B + S_English-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_Abkhasian-1B + S_Georgian-2B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Finnish-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_Abkhasian-1B + S_Hungarian-2A Discordant SGDP 136,555,141 – 136,762,052 206,910.5 0.02601890 9 100.3170 1,794.3
S_North_Ossetian-2B + S_Saami-2B Discordant SGDP 136,555,141 – 136,976,283 421,142.0 0.25682418 30 203.1482 2,953.5
S_Abkhasian-1B + S_Druze-1A Discordant SGDP 136,080,619 – 136,566,051 485,431.5 0.04702322 18 234.0071 1,538.4
S_North_Ossetian-2B + S_Icelandic-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_Abkhasian-1B + S_Palestinian-1A Discordant SGDP 136,555,141 – 136,762,052 206,910.5 0.02601890 8 100.3170 1,594.9
S_North_Ossetian-2B + S_Jordanian-3A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 18 85.6250 4,204.4
S_Abkhasian-1B + S_Sardinian-1A Discordant SGDP 135,597,516 – 136,785,841 1,188,325.0 0.26173649 25 571.3960 875.0
S_North_Ossetian-2B + S_Orcadian-2A Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 4 42.7979 1,869.2
S_Abkhasian-1B + S_North_Ossetian-2A Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 30 387.8574 1,547.0
S_North_Ossetian-2B + S_Tajik-2A Discordant SGDP 136,556,402 – 137,629,015 1,072,613.5 0.96585764 54 515.8545 2,093.6
S_Abkhasian-1B + S_Adygei-1A Discordant SGDP 135,597,516 – 136,566,051 968,535.0 0.22556769 38 465.8968 1,631.3
S_North_Ossetian-2B + B_Crete-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 14 85.6250 3,270.1
S_Abkhasian-1B + S_Adygei-2B Discordant SGDP 135,597,516 – 136,566,051 968,535.0 0.22556769 45 465.8968 1,931.8
S_North_Ossetian-2B + S_Pima-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_Abkhasian-1B + S_Spanish-1A Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 33 387.8574 1,701.7
S_North_Ossetian-2B + S_Chukchi-1B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 4 42.7979 1,869.2
S_Abkhasian-1B + S_Yemenite_Jew-1A Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 38 387.8574 1,959.5
S_North_Ossetian-2B + S_Brahmin-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 17 85.6250 3,970.8
S_Abkhasian-1B + B_Sardinian-3A Discordant SGDP 135,760,098 – 136,785,841 1,025,743.0 0.10319507 7 493.3566 283.8
S_North_Ossetian-2B + S_Burusho-2B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 4 42.7979 1,869.2
S_Abkhasian-1B + B_Sardinian-3B Discordant SGDP 135,597,516 – 136,566,051 968,535.0 0.22556769 37 465.8968 1,588.3
S_North_Ossetian-2B + S_Punjabi-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_Abkhasian-1B + B_Karitiana-3B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Punjabi-4A Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 4 42.7979 1,869.2
S_Abkhasian-1B + S_Chane-1A Discordant SGDP 136,555,141 – 136,762,052 206,910.5 0.02601890 10 100.3170 1,993.7
S_North_Ossetian-2B + S_Atayal-1A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_Abkhasian-1B + S_Pima-1B Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 41 387.8574 2,114.2
S_North_Ossetian-2B + S_English-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_Abkhasian-1B + S_Pima-2B Discordant SGDP 135,760,098 – 136,566,051 805,953.0 0.06702628 36 387.8574 1,856.4
S_North_Ossetian-2B + S_BantuKenya-1A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Mozabite-1A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Estonian-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Mixtec-2B Discordant SGDP 136,555,141 – 136,642,220 87,079.0 0.01737440 3 42.7979 1,401.9
S_North_Ossetian-2B + S_Finnish-3A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Mongola-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Saami-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Tubalar-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 17 85.6250 3,970.8
S_North_Ossetian-2B + S_French-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 17 85.6250 3,970.8
S_North_Ossetian-2B + S_Tlingit-1B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Greek-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Aleut-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Iranian-1B Discordant SGDP 136,394,329 – 136,566,051 171,722.0 0.02943990 16 83.4266 3,835.7
S_North_Ossetian-2B + S_Cambodian-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 20 85.6250 4,671.5
S_North_Ossetian-2B + S_Tuscan-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Naxi-2B Discordant SGDP 136,555,141 – 136,587,056 31,914.5 0.00700724 4 16.3190 4,902.3
S_North_Ossetian-2B + S_Kyrgyz-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Dai-3B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Orcadian-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 19 85.6250 4,438.0
S_North_Ossetian-2B + S_Miao-2A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Lezgin-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Uygur-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 17 85.6250 3,970.8
S_North_Ossetian-2B + S_Spanish-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Xibo-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Turkish-1B Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Yi-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Yemenite_Jew-1B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 19 85.6250 4,438.0
S_North_Ossetian-2B + S_Mozabite-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 20 85.6250 4,671.5
S_North_Ossetian-2B + B_French-3B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Xibo-2A Discordant SGDP 136,566,014 – 136,566,051 36.5 0.00000127 2 1.0175 39,311.3
S_North_Ossetian-2B + S_Piapoco-1A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
S_North_Ossetian-2B + S_Kinh-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 18 85.6250 4,204.4
S_North_Ossetian-2B + S_Pima-2A Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 15 85.6250 3,503.7
S_North_Ossetian-2B + S_Dusun-2B Discordant SGDP 136,389,749 – 136,566,051 176,302.0 0.03246927 16 85.6250 3,737.2
View as figure
Data shown in this table can be downloaded from this page.
α Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
β Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
Mean TMRCA Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default.
 

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