HumanGenomeDating
Download profile data
for this variant in csv format

Genealogical Estimation of Variant Age (GEVA)

Inference of the ancestral origin of a genetic variant at a single locus

Unmatched Variant ID, using internal ID instead:
X436631241
Alleles:
reference
T
alternate
C
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
Chromosome 2   position  136,631,241  (GRCh37)
Allele frequency in   SGDP
Sample 98.6%
1.4%
AFR 100.0%
0.0%
AMR 88.6%
11.4%
CAS 100.0%
0.0%
EAS 97.9%
2.1%
OCN 100.0%
0.0%
SAS 100.0%
0.0%
WEA 99.3%
0.7%
reference ← allele frequency → alternate
Age estimation summary Recombination clock
Data source Estimated age of C allele # pairs = concordant + discordant Quality score
 Genomes in SGDP32.4 generations 114  =  22  +  920.045
Pairwise results table Recombination clock
Haplotype pair Pair type Data source Breakpoint positions Physical length (bp) Genetic Length (cM) α β Mean TMRCA (generations)
S_Zapotec-2B + S_Norwegian-1A Concordant SGDP 135,170,533136,781,557 1,611,024.5 0.67014098 3 537.1128 111.7
S_Cambodian-2A + S_Norwegian-1A Concordant SGDP 136,489,176136,788,485 299,309.0 0.08152040 3 66.2163 906.1
S_Zapotec-2A + S_Norwegian-1A Concordant SGDP 135,727,306136,778,638 1,051,332.0 0.23041732 3 185.3339 323.7
S_Zapotec-2B + S_Cambodian-2A Concordant SGDP 135,755,745136,781,557 1,025,812.0 0.16248506 3 130.9880 458.1
S_Surui-2B + S_Zapotec-2B Concordant SGDP 136,493,766136,781,557 287,791.5 0.04338087 3 35.7047 1,680.5
S_Surui-2B + S_Norwegian-1A Concordant SGDP 135,542,762136,851,938 1,309,175.5 0.50539489 3 405.3159 148.0
S_Mixe-3B + S_Norwegian-1A Concordant SGDP 135,216,100136,778,638 1,562,537.5 0.59015006 3 473.1201 126.8
S_Surui-2B + S_Mixe-3B Concordant SGDP 135,542,762136,778,638 1,235,875.5 0.33254240 3 267.0339 224.7
S_Mixe-3B + S_Cambodian-2A Concordant SGDP 136,489,176136,778,638 289,461.5 0.04263593 3 35.1087 1,709.0
S_Mixe-3B + S_Cambodian-2B Concordant SGDP 136,489,176136,778,638 289,461.5 0.04263593 3 35.1087 1,709.0
S_Mixe-3B + S_Zapotec-2B Concordant SGDP 135,216,100136,778,638 1,562,537.5 0.59015006 3 473.1201 126.8
S_Mixe-3B + S_Zapotec-2A Concordant SGDP 135,734,431136,788,083 1,053,652.0 0.25565025 3 205.5202 291.9
S_Mixe-3B + S_Mixe-3A Concordant SGDP 135,727,306136,778,638 1,051,332.0 0.23041732 3 185.3339 323.7
S_Cambodian-2B + S_Norwegian-1A Concordant SGDP 136,489,176136,787,770 298,593.5 0.06994256 3 56.9540 1,053.5
S_Zapotec-2A + S_Zapotec-2B Concordant SGDP 136,493,766136,976,448 482,682.0 0.27212041 3 218.6963 274.4
S_Surui-2B + S_Mixe-3A Concordant SGDP 135,727,306137,123,261 1,395,955.5 0.82218703 3 658.7496 91.1
S_Zapotec-2A + S_Cambodian-2A Concordant SGDP 136,489,176136,778,638 289,461.5 0.04263593 3 35.1087 1,709.0
S_Surui-2B + S_Zapotec-2A Concordant SGDP 135,734,431136,778,638 1,044,206.5 0.22327073 3 179.6166 334.0
S_Zapotec-2A + S_Cambodian-2B Concordant SGDP 136,489,176136,778,638 289,461.5 0.04263593 3 35.1087 1,709.0
S_Surui-2B + S_Cambodian-2B Concordant SGDP 136,489,176136,787,770 298,593.5 0.06994256 3 56.9540 1,053.5
S_Mixe-3A + S_Norwegian-1A Concordant SGDP 135,727,306136,851,938 1,124,632.0 0.40326981 3 323.6158 185.4
S_Mixe-3A + S_Cambodian-2B Concordant SGDP 136,489,176136,787,770 298,593.5 0.06994256 3 56.9540 1,053.5
S_Surui-2B + S_Punjabi-4B Discordant SGDP 135,597,516137,032,475 1,434,959.0 0.58652654 3 470.2212 127.6
S_Norwegian-1A + S_Orcadian-2B Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Norwegian-1A + S_Saharawi-2A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_French-2A Discordant SGDP 135,760,098136,821,414 1,061,316.0 0.17130701 3 138.0456 434.6
S_Norwegian-1A + S_Iranian-1A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Mixe-3A + S_Tlingit-1A Discordant SGDP 135,760,098136,821,414 1,061,316.0 0.17130701 3 138.0456 434.6
S_Norwegian-1A + S_Finnish-1A Discordant SGDP 135,483,681136,822,338 1,338,657.0 0.42721690 3 342.7735 175.0
S_Cambodian-2A + S_Japanese-1A Discordant SGDP 135,760,398136,785,841 1,025,443.0 0.10255580 3 83.0446 722.5
S_Cambodian-2A + S_Atayal-1B Discordant SGDP 136,489,176136,785,841 296,664.5 0.04950107 3 40.6009 1,477.8
S_Mixe-3A + S_Balochi-1A Discordant SGDP 135,760,098136,976,283 1,216,185.5 0.31932188 3 256.4575 234.0
S_Mixe-3A + S_Brahui-1B Discordant SGDP 135,760,098136,976,283 1,216,185.5 0.31932188 3 256.4575 234.0
S_Mixe-3A + S_Xibo-2B Discordant SGDP 135,760,098136,785,841 1,025,743.0 0.10319507 3 83.5561 718.1
S_Mixe-3A + S_Xibo-1A Discordant SGDP 135,344,431136,785,841 1,441,410.0 0.38887572 3 312.1006 192.2
S_Mixe-3A + S_Miao-1A Discordant SGDP 135,760,098136,785,841 1,025,743.0 0.10319507 3 83.5561 718.1
S_Surui-2B + S_Bergamo-2B Discordant SGDP 135,597,516136,976,283 1,378,767.5 0.47786329 3 383.2906 156.5
S_Cambodian-2A + B_Crete-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Surui-2B + B_French-3A Discordant SGDP 135,760,098136,821,414 1,061,316.0 0.17130701 3 138.0456 434.6
S_Cambodian-2B + S_Miao-2A Discordant SGDP 135,954,725136,785,841 831,115.5 0.08781031 3 71.2483 842.1
S_Norwegian-1A + S_Estonian-2A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Cambodian-2B + S_Dusun-1A Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
S_Norwegian-1A + S_Saami-1A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Cambodian-2B + S_Papuan-5B Discordant SGDP 135,340,792136,646,325 1,305,532.5 0.37249769 3 298.9982 200.7
S_Norwegian-1A + S_Basque-1B Discordant SGDP 135,216,236136,821,414 1,605,177.5 0.66362260 3 531.8981 112.8
S_Norwegian-1A + S_Mozabite-1A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_Norwegian-1B Discordant SGDP 136,023,831136,822,338 798,507.5 0.15669601 3 126.3568 474.8
S_Norwegian-1A + S_Dai-3B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_North_Ossetian-1B Discordant SGDP 135,340,792136,822,338 1,481,546.0 0.46556231 3 373.4499 160.7
S_Norwegian-1A + S_Mozabite-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Surui-2B + S_Maori-1B Discordant SGDP 135,597,516136,976,283 1,378,767.5 0.47786329 3 383.2906 156.5
S_Norwegian-1A + S_Sindhi-2B Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Surui-2B + S_Finnish-3B Discordant SGDP 135,597,516136,821,414 1,223,898.0 0.32984843 3 264.8787 226.5
S_Norwegian-1A + S_Bulgarian-1A Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
S_Surui-2B + S_Spanish-1B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_English-2A Discordant SGDP 135,282,993136,822,338 1,539,345.0 0.57421678 3 460.3734 130.3
S_Mixe-3A + S_Makrani-2A Discordant SGDP 135,760,098136,976,283 1,216,185.5 0.31932188 3 256.4575 234.0
S_Mixe-3A + S_Mongola-2B Discordant SGDP 135,340,792136,762,052 1,421,259.5 0.38028236 3 305.2259 196.6
S_Cambodian-2A + S_Burmese-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Mixe-3A + S_Czech-2A Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
S_Cambodian-2A + S_Kyrgyz-1B Discordant SGDP 135,217,238136,785,841 1,568,603.0 0.59179792 3 474.4383 126.5
S_Mixe-3A + S_Jordanian-3A Discordant SGDP 135,941,976136,821,414 879,438.0 0.15649117 3 126.1929 475.5
S_Cambodian-2B + S_Mixtec-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Mixe-3A + S_Lezgin-2A Discordant SGDP 135,760,098136,785,841 1,025,743.0 0.10319507 3 83.5561 718.1
S_Cambodian-2B + S_Xibo-1B Discordant SGDP 135,954,725136,762,052 807,326.5 0.07313183 3 59.5055 1,008.3
S_Mixe-3A + S_Lezgin-1B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Cambodian-2B + S_Papuan-6B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Mixe-3A + S_Spanish-2B Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
S_Cambodian-2B + S_Mala-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Mixe-3A + S_Yemenite_Jew-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_Aleut-2B Discordant SGDP 135,216,236136,821,414 1,605,177.5 0.66362260 3 531.8981 112.8
S_Mixe-3A + B_Mixe-1A Discordant SGDP 135,171,548136,976,283 1,804,735.0 0.88085387 3 705.6831 85.0
S_Norwegian-1A + S_Chukchi-1A Discordant SGDP 134,729,034136,822,338 2,093,304.0 1.34536020 3 1,077.2882 55.7
S_Mixe-3A + S_Piapoco-2B Discordant SGDP 136,489,176136,785,841 296,664.5 0.04950107 3 40.6009 1,477.8
S_Norwegian-1A + S_Brahmin-2B Discordant SGDP 135,778,044136,822,338 1,044,294.5 0.16506012 3 133.0481 451.0
S_Mixe-3B + S_Daur-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_Punjabi-2B Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Mixe-3B + S_Yi-2B Discordant SGDP 135,760,098136,631,242 871,144.5 0.07817721 3 63.5418 944.3
S_Norwegian-1A + S_English-1B Discordant SGDP 135,216,236136,821,414 1,605,177.5 0.66362260 3 531.8981 112.8
S_Mixe-3B + S_Kinh-2A Discordant SGDP 135,760,098136,761,879 1,001,781.5 0.08799281 3 71.3942 840.4
S_Norwegian-1A + S_English-2B Discordant SGDP 135,216,236136,822,338 1,606,102.0 0.66611213 3 533.8897 112.4
S_Mixe-3B + S_Pathan-2A Discordant SGDP 135,760,098136,761,879 1,001,781.5 0.08799281 3 71.3942 840.4
S_Norwegian-1A + S_Estonian-1B Discordant SGDP 135,760,098136,821,414 1,061,316.0 0.17130701 3 138.0456 434.6
S_Mixe-3B + S_Samaritan-1A Discordant SGDP 135,760,098136,761,879 1,001,781.5 0.08799281 3 71.3942 840.4
S_Norwegian-1A + S_Finnish-3B Discordant SGDP 134,765,570136,822,338 2,056,768.5 1.33035284 3 1,065.2823 56.3
S_Mixe-3B + S_Kyrgyz-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + S_Saami-2A Discordant SGDP 135,340,792136,821,414 1,480,621.5 0.46307279 3 371.4582 161.5
S_Mixe-3B + S_Piapoco-1A Discordant SGDP 135,760,098136,761,879 1,001,781.5 0.08799281 3 71.3942 840.4
S_Norwegian-1A + S_French-2B Discordant SGDP 135,760,098136,821,414 1,061,316.0 0.17130701 3 138.0456 434.6
S_Zapotec-2A + S_Yadava-2A Discordant SGDP 136,489,176136,976,283 487,107.0 0.26562788 3 213.5023 281.0
S_Norwegian-1A + S_Icelandic-1B Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Zapotec-2B + S_Zapotec-1A Discordant SGDP 136,493,766137,032,475 538,709.0 0.37317547 3 299.5404 200.3
S_Norwegian-1A + S_Tuscan-2B Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Zapotec-2B + S_Tubalar-2A Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
S_Norwegian-1A + S_Orcadian-1B Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Zapotec-2B + S_Uygur-1A Discordant SGDP 136,493,766136,762,052 268,286.0 0.03370694 3 27.9656 2,145.5
S_Norwegian-1A + S_Polish-1A Discordant SGDP 135,282,993136,822,338 1,539,345.0 0.57421678 3 460.3734 130.3
S_Zapotec-2B + S_Dusun-2A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Norwegian-1A + B_French-3A Discordant SGDP 135,760,098136,822,338 1,062,240.5 0.17379654 3 140.0372 428.5
S_Zapotec-2B + S_Papuan-12B Discordant SGDP 135,636,692136,976,283 1,339,591.0 0.46977193 3 376.8175 159.2
S_Surui-2B + S_Mixtec-1A Discordant SGDP 135,760,098137,032,475 1,272,377.0 0.42798512 3 343.3881 174.7
S_Zapotec-2B + S_Papuan-2A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Surui-2B + S_Hazara-1B Discordant SGDP 135,597,516136,976,283 1,378,767.5 0.47786329 3 383.2906 156.5
S_Zapotec-2B + S_Burusho-2B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Surui-2B + S_English-1B Discordant SGDP 135,597,516136,822,338 1,224,822.5 0.33233796 3 266.8704 224.8
S_Cambodian-2A + S_Altaian-1A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Surui-2B + S_Greek-2A Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Cambodian-2A + S_Miao-2B Discordant SGDP 136,489,176136,785,841 296,664.5 0.04950107 3 40.6009 1,477.8
S_Surui-2B + S_Orcadian-1B Discordant SGDP 135,760,098136,976,283 1,216,185.5 0.31932188 3 256.4575 234.0
S_Cambodian-2A + S_Yi-1B Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
S_Surui-2B + S_Tajik-2B Discordant SGDP 135,597,516136,976,283 1,378,767.5 0.47786329 3 383.2906 156.5
S_Cambodian-2A + S_Tujia-1B Discordant SGDP 135,760,098136,785,841 1,025,743.0 0.10319507 3 83.5561 718.1
S_Surui-2B + S_Karitiana-1B Discordant SGDP 136,631,239136,631,242 3.5 0.00000115 3 1.0009 59,944.9
S_Cambodian-2A + S_Xibo-2A Discordant SGDP 135,760,098136,762,052 1,001,954.0 0.08851659 3 71.8133 835.5
Data shown in this table can be downloaded from this page.
α Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
β Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
Mean TMRCA Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default.