HumanGenomeDating
Atlas of Variant Age
Search
Examples: LCT, MCM6, EDAR, ZEB1
Shared Ancestry Database
TGP
1000 Genomes Project
Populations: 26
Individuals: 2,535
Ancestry analyses:565,507,800
Watch movie
SGDP
Simons Genome Diversity Project
Populations: 130
Individuals: 278
Ancestry analyses:6,800,992
Watch movie
Shared Ancestry Movies
About
Bulk downloads
Frequently Asked Questions
Citation
Download profile data
for this variant in csv format

Genealogical Estimation of Variant Age (GEVA)

Inference of the ancestral origin of a genetic variant at a single locus

rs112108654
Alleles:
reference
T
ancestral
alternate
G
derived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome 10   position  31,672,979  (GRCh37) Explore rs112108654 on Ensembl!
Allele frequency in   SGDP ⇪
Sample 98.4%
1.6%
AFR 89.8%
10.2%
AMR 100.0%
0.0%
CAS 100.0%
0.0%
EAS 100.0%
0.0%
OCN 100.0%
0.0%
SAS 100.0%
0.0%
WEA 100.0%
0.0%
reference ← allele frequency → alternate
Select clock model
  Mutation clock
  Recombination clock
  Joint clock
Age estimation summary Joint clock
Data source Estimated age of G allele # pairs = concordant + discordant Quality score
    Genomes in SGDP12,009.5 generations 123  =  25  +  981.000
Pairwise results table Joint clock
Haplotype pair Pair type Data source Breakpoint positions Physical length (bp) Genetic Length (cM) α β Mean TMRCA (generations)
S_Ju_hoan_North-2B + S_Ju_hoan_North-1B Concordant SGDP 31,556,603 – 31,870,414 313,810.5 0.04203703 20 185.2587 2,159.1
S_Ju_hoan_North-2B + B_Ju_hoan_North-4B Concordant SGDP 31,556,603 – 31,873,306 316,702.5 0.10924376 26 240.4122 2,163.0
S_Khomani_San-2A + S_Khomani_San-1B Concordant SGDP 30,998,177 – 31,824,938 826,760.5 0.47080762 52 774.4911 1,342.8
S_Ju_hoan_North-2A + S_Khomani_San-1B Concordant SGDP 31,557,667 – 31,906,050 348,382.5 0.13191199 53 273.7532 3,872.1
S_Ju_hoan_North-1B + B_Ju_hoan_North-4B Concordant SGDP 31,068,515 – 31,870,414 801,899.0 0.36691039 36 679.4398 1,059.7
S_Ju_hoan_North-1B + S_Khomani_San-1B Concordant SGDP 31,557,667 – 31,906,050 348,382.5 0.13191199 55 273.7532 4,018.2
S_Ju_hoan_North-3B + S_Khomani_San-2A Concordant SGDP 31,480,954 – 31,824,938 343,983.5 0.04086920 38 198.8074 3,822.8
S_Ju_hoan_North-1A + S_Khomani_San-2A Concordant SGDP 31,107,575 – 31,824,938 717,363.0 0.29153703 103 578.5639 3,560.5
S_Ju_hoan_North-3B + S_Ju_hoan_North-1B Concordant SGDP 31,557,667 – 31,951,947 394,280.0 0.25042696 60 390.5960 3,072.2
S_Ju_hoan_North-3B + B_Ju_hoan_North-4B Concordant SGDP 31,557,667 – 31,841,841 284,174.0 0.01321669 33 147.9769 4,460.2
S_Ju_hoan_North-3A + B_Ju_hoan_North-4B Concordant SGDP 31,557,667 – 31,841,841 284,174.0 0.01321669 37 147.9769 5,000.8
S_Ju_hoan_North-3A + S_Ju_hoan_North-1B Concordant SGDP 31,557,667 – 31,841,841 284,174.0 0.01321669 35 147.9769 4,730.5
S_Ju_hoan_North-3A + S_Ju_hoan_North-2B Concordant SGDP 31,557,667 – 31,840,315 282,647.5 0.01290321 49 146.9934 6,667.0
S_Ju_hoan_North-2B + S_Khomani_San-2A Concordant SGDP 31,557,667 – 31,824,938 267,270.5 0.01140339 70 138.4125 10,114.7
S_Ju_hoan_North-3B + S_Khomani_San-1B Concordant SGDP 31,480,954 – 31,910,782 429,827.5 0.25894213 15 414.4709 723.8
S_Ju_hoan_North-2B + S_Khomani_San-1B Concordant SGDP 31,557,667 – 31,840,315 282,647.5 0.01290321 50 146.9934 6,803.0
S_Ju_hoan_North-2A + S_Ju_hoan_North-1A Concordant SGDP 31,557,667 – 31,906,050 348,382.5 0.13191199 50 273.7532 3,652.9
S_Ju_hoan_North-1A + S_Khomani_San-1B Concordant SGDP 31,107,575 – 32,162,772 1,055,197.0 0.71285433 68 1,077.7780 1,261.9
S_Ju_hoan_North-2A + S_Ju_hoan_North-1B Concordant SGDP 31,068,515 – 33,707,610 2,639,095.5 1.74323778 137 2,662.3561 1,029.2
S_Ju_hoan_North-1B + S_Khomani_San-2A Concordant SGDP 31,557,667 – 31,824,938 267,270.5 0.01140339 56 138.4125 8,091.8
S_Ju_hoan_North-2A + S_Khomani_San-2A Concordant SGDP 31,557,667 – 31,795,978 238,310.5 0.01002565 43 123.4096 6,968.7
S_Khomani_San-2A + B_Ju_hoan_North-4B Concordant SGDP 31,557,667 – 31,824,938 267,270.5 0.01140339 59 138.4125 8,525.2
S_Khomani_San-1B + B_Ju_hoan_North-4B Concordant SGDP 31,557,667 – 31,841,841 284,174.0 0.01321669 38 147.9769 5,135.9
S_Ju_hoan_North-3A + S_Ju_hoan_North-3B Concordant SGDP 31,408,348 – 31,870,414 462,066.0 0.19978861 30 382.6226 1,568.1
S_Ju_hoan_North-3A + S_Ju_hoan_North-2A Concordant SGDP 31,557,667 – 31,841,841 284,174.0 0.01321669 33 147.9769 4,460.2
S_Khomani_San-2A + S_Kapu-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Papuan-9A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Orcadian-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Icelandic-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Czech-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Sindhi-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Madiga-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Tu-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Mansi-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-14B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Maori-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + B_Dai-4B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Irula-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Uygur-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Mala-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Korean-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Pathan-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Ami-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Armenian-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + B_Australian-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Saami-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Maori-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Iranian-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_BedouinB-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Tuscan-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Khonda_Dora-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Yemenite_Jew-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Brahmin-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Pima-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Georgian-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-4A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Iranian-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-12A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Kyrgyz-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Sardinian-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Lezgin-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Han-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3A + S_Spanish-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Oroqen-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Mozabite-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_She-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + B_Australian-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Burmese-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + B_Australian-4A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Thai-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Papuan-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Dusun-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Burusho-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Bougainville-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Hungarian-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Chukchi-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Icelandic-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Relli-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Russian-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Mala-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + S_Turkish-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Brahmin-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-3B + B_Sardinian-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Makrani-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-2A + S_Hazara-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Kalash-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-2A + S_Kyrgyz-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Abkhasian-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-2B + S_Jordanian-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Bulgarian-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-2B + S_Chechen-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Estonian-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1A + S_Papuan-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Saami-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1A + S_Kalash-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Icelandic-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1A + S_Polish-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Druze-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1B + S_Tubalar-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Sardinian-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1B + S_Papuan-3A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Jordanian-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1B + S_Papuan-7A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Yemenite_Jew-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Ju_hoan_North-1B + S_Papuan-7B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Yemenite_Jew-1A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Mixe-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + B_French-3A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Mongola-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Tu-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Tubalar-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-5B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Yakut-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-4B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Even-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-9B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Even-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Papuan-2A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Yakut-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + S_Finnish-1B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Aleut-2B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-1B + B_Papuan-15A Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
S_Khomani_San-2A + S_Naxi-3B Discordant SGDP 31,672,973 – 31,673,025 52.0 0.00000014 4 1.0251 78,043.3
View as figure
Data shown in this table can be downloaded from this page.
α Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
β Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
Mean TMRCA Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default.
 

The human.genome.dating database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of human.genome.dating are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

human.genome.dating © 2019 - 2026 Contact Terms & Conditions This website does not use cookies and does not collect any personal information about you.