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Genealogical Estimation of Variant Age (GEVA)

Inference of the ancestral origin of a genetic variant at a single locus

rs113538248
Alleles:
reference
A
ancestral
alternate
G
derived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
Allele frequency in   SGDP
Sample 98.0%
2.0%
AFR 87.5%
12.5%
AMR 100.0%
0.0%
CAS 100.0%
0.0%
EAS 100.0%
0.0%
OCN 100.0%
0.0%
SAS 100.0%
0.0%
WEA 100.0%
0.0%
reference ← allele frequency → alternate
Age estimation summary Joint clock
Data source Estimated age of G allele # pairs = concordant + discordant Quality score
 Genomes in SGDP21,461.4 generations 139  =  42  +  971.000
Pairwise results table Joint clock
Haplotype pair Pair type Data source Breakpoint positions Physical length (bp) Genetic Length (cM) α β Mean TMRCA (generations)
S_Ju_hoan_North-2A + B_Ju_hoan_North-4B Concordant SGDP 31,054,92631,870,414 815,488.0 0.38557722 33 700.8960 941.7
S_Ju_hoan_North-3B + S_Khomani_San-1B Concordant SGDP 31,480,95431,910,782 429,827.5 0.25894213 15 414.4709 723.8
S_Ju_hoan_North-2A + S_Ju_hoan_North-1A Concordant SGDP 31,557,66731,906,050 348,382.5 0.13191199 50 273.7532 3,652.9
S_Ju_hoan_North-3B + S_Ju_hoan_North-2B Concordant SGDP 31,557,66731,840,315 282,647.5 0.01290321 45 146.9934 6,122.7
S_Ju_hoan_North-3B + B_Ju_hoan_North-4B Concordant SGDP 31,557,66731,841,841 284,174.0 0.01321669 33 147.9769 4,460.2
S_Ju_hoan_North-1A + S_Khomani_San-1B Concordant SGDP 31,107,57532,162,772 1,055,197.0 0.71285433 68 1,077.7780 1,261.9
S_Khomani_San-2B + S_Khomani_San-1B Concordant SGDP 31,826,46032,146,479 320,018.5 0.41915186 21 489.9304 857.3
S_Mbuti-3A + S_Khomani_San-2B Concordant SGDP 31,826,46031,827,127 667.0 0.00014209 4 1.4338 55,794.5
S_Mbuti-3A + S_Khomani_San-1B Concordant SGDP 31,778,45231,827,127 48,675.0 0.00315818 9 26.8905 6,693.8
S_Mbuti-3A + S_Ju_hoan_North-1B Concordant SGDP 31,727,31931,827,533 100,214.0 0.00487860 11 53.0056 4,150.5
S_Mbuti-3A + B_Ju_hoan_North-4B Concordant SGDP 31,727,31931,827,533 100,214.0 0.00487860 12 53.0056 4,527.8
S_Mbuti-3A + S_Ju_hoan_North-1A Concordant SGDP 31,778,45231,827,127 48,675.0 0.00315818 9 26.8905 6,693.8
S_Mbuti-3A + S_Ju_hoan_North-2A Concordant SGDP 31,727,31931,827,533 100,214.0 0.00487860 12 53.0056 4,527.8
S_Mbuti-3A + S_Ju_hoan_North-3B Concordant SGDP 31,778,45231,827,127 48,675.0 0.00315818 9 26.8905 6,693.8
S_Ju_hoan_North-2B + S_Ju_hoan_North-1B Concordant SGDP 31,556,60331,870,414 313,810.5 0.04203703 20 185.2587 2,159.1
S_Mbuti-2A + S_Ju_hoan_North-3A Concordant SGDP 31,776,20831,827,533 51,325.0 0.00330794 11 28.2824 7,778.7
S_Ju_hoan_North-1A + B_Ju_hoan_North-4B Concordant SGDP 31,557,66731,841,841 284,174.0 0.01321669 36 147.9769 4,865.6
S_Mbuti-2A + S_Ju_hoan_North-3B Concordant SGDP 31,816,03931,827,127 11,088.0 0.00137808 4 7.4247 10,774.8
S_Ju_hoan_North-1B + S_Khomani_San-1B Concordant SGDP 31,557,66731,906,050 348,382.5 0.13191199 55 273.7532 4,018.2
S_Mbuti-2A + S_Ju_hoan_North-2B Concordant SGDP 31,792,74831,870,414 77,666.0 0.03250002 19 64.2797 5,911.7
S_Ju_hoan_North-3B + S_Ju_hoan_North-3A Concordant SGDP 31,408,34831,870,414 462,066.0 0.19978861 31 382.6226 1,620.4
S_Mbuti-2A + S_Ju_hoan_North-1A Concordant SGDP 31,816,03931,827,127 11,088.0 0.00137808 4 7.4247 10,774.8
S_Ju_hoan_North-3B + S_Ju_hoan_North-1B Concordant SGDP 31,557,66731,951,947 394,280.0 0.25042696 60 390.5960 3,072.2
S_Mbuti-2A + S_Ju_hoan_North-1B Concordant SGDP 31,727,31931,870,414 143,094.5 0.03449380 27 97.2804 5,551.0
S_Ju_hoan_North-3B + S_Khomani_San-2B Concordant SGDP 31,826,46031,910,782 84,321.5 0.21758664 8 215.5436 742.3
S_Mbuti-2A + B_Ju_hoan_North-4B Concordant SGDP 31,727,31931,870,414 143,094.5 0.03449380 31 97.2804 6,373.3
S_Ju_hoan_North-2A + S_Ju_hoan_North-2B Concordant SGDP 31,556,60331,870,414 313,810.5 0.04203703 26 185.2587 2,806.9
S_Mbuti-2A + S_Khomani_San-2B Concordant SGDP 31,826,46031,827,127 667.0 0.00014209 4 1.4338 55,794.5
S_Ju_hoan_North-2A + S_Ju_hoan_North-1B Concordant SGDP 31,068,51533,707,610 2,639,095.5 1.74323778 138 2,662.3561 1,036.7
S_Mbuti-2A + S_Khomani_San-1B Concordant SGDP 31,816,03931,827,127 11,088.0 0.00137808 4 7.4247 10,774.8
S_Ju_hoan_North-2A + S_Khomani_San-1B Concordant SGDP 31,557,66731,906,050 348,382.5 0.13191199 53 273.7532 3,872.1
S_Ju_hoan_North-3A + S_Ju_hoan_North-2A Concordant SGDP 31,557,66731,841,841 284,174.0 0.01321669 33 147.9769 4,460.2
S_Ju_hoan_North-2B + S_Khomani_San-2B Concordant SGDP 31,826,46031,840,315 13,854.5 0.00101353 8 8.4610 18,910.3
S_Ju_hoan_North-3A + S_Ju_hoan_North-1A Concordant SGDP 31,444,03531,870,414 426,379.0 0.16908465 21 340.9296 1,231.9
S_Ju_hoan_North-1A + S_Khomani_San-2B Concordant SGDP 31,826,46032,298,407 471,947.0 0.43149170 33 572.7279 1,152.4
S_Ju_hoan_North-3A + S_Khomani_San-2B Concordant SGDP 31,826,46031,870,414 43,953.5 0.02990491 6 46.0216 2,607.5
S_Ju_hoan_North-1B + S_Ju_hoan_North-1A Concordant SGDP 31,557,66731,906,050 348,382.5 0.13191199 52 273.7532 3,799.0
S_Ju_hoan_North-3A + S_Khomani_San-1B Concordant SGDP 31,092,46831,870,414 777,946.0 0.33267586 49 640.5548 1,529.9
S_Khomani_San-2B + B_Ju_hoan_North-4B Concordant SGDP 31,826,46031,841,841 15,381.0 0.00132701 7 9.4445 14,823.5
S_Khomani_San-1B + B_Ju_hoan_North-4B Concordant SGDP 31,557,66731,841,841 284,174.0 0.01321669 38 147.9769 5,135.9
S_Mbuti-3A + S_Mbuti-2A Concordant SGDP 31,480,07432,054,608 574,534.0 0.42992166 79 620.7136 2,545.5
S_Mbuti-3A + S_Ju_hoan_North-3A Concordant SGDP 31,778,45231,827,533 49,081.0 0.00330581 7 27.2035 5,146.4
S_Ju_hoan_North-3A + S_Spanish-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Iraqi_Jew-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Quechua-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Kapu-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-5B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-12B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + B_Papuan-15B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2A + S_Hazara-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Polish-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Chechen-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Sardinian-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Bergamo-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_French-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + B_Australian-4A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2A + S_Norwegian-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Bougainville-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2A + S_Chane-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-14B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2B + S_Albanian-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_English-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2B + S_Adygei-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Aleut-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Yakut-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Basque-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Relli-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Karitiana-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Mala-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Lezgin-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Madiga-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Ami-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Finnish-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Jordanian-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1B + S_Chukchi-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-4A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1B + S_Luhya-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Papuan-7B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1B + S_Orcadian-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Mansi-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Khonda_Dora-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Brahui-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Mbuti-3A + S_Yakut-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Estonian-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Mbuti-3A + S_Tu-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Greek-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Mozabite-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Sardinian-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Tubalar-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Orcadian-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + B_Australian-4A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Russian-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Maori-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + S_Turkish-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-10A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3B + B_Sardinian-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-6A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2A + S_Punjabi-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-4A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2A + B_Crete-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-7B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2B + S_Tubalar-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-9A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2B + S_Jordanian-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-12A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-2B + S_Turkish-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Papuan-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Burmese-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Brahmin-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Somali-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Kalash-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Brahmin-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Burusho-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Estonian-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Estonian-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + S_Bergamo-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Finnish-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1A + B_Dinka-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Georgian-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1B + S_Mala-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Georgian-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1B + S_Palestinian-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Greek-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-1B + B_French-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Hungarian-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Even-3A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Icelandic-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Korean-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Iranian-2B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Albanian-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_BedouinB-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Icelandic-1A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Kyrgyz-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Sardinian-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Orcadian-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Khomani_San-1B + S_Piapoco-2A Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
S_Ju_hoan_North-3A + S_Polish-1B Discordant SGDP 31,826,61031,826,670 60.0 0.00001118 4 1.0377 77,090.3
Data shown in this table can be downloaded from this page.
α Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
β Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default).
Mean TMRCA Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default.