Genealogical Estimation of Variant Age (GEVA)
Inference of the ancestral origin of a genetic variant at a single locus
rs372508878
Alleles:
reference
Cancestral
alternate
Tderived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome 
Explore
2
position 136,564,601 (GRCh37)
Explore rs372508878 on Ensembl!
Allele frequency in SGDP ⇪
| Sample | 98.9% |
1.1% |
|
AFR |
93.2% |
6.8% |
|
AMR |
100.0% |
0.0% |
|
CAS |
100.0% |
0.0% |
|
EAS |
100.0% |
0.0% |
|
OCN |
100.0% |
0.0% |
|
SAS |
100.0% |
0.0% |
|
WEA |
100.0% |
0.0% |
|
| reference | ← allele frequency → | alternate |
Select clock model
Age estimation summary
| Data source | Estimated age of T allele |
# pairs = concordant + discordant | Quality score |
|---|---|---|---|
| Genomes in SGDP | 8,648.0 generations | 107 = 8 + 99 | 0.960 |
Pairwise results table
| Haplotype pair | Pair type | Data source | Breakpoint positions | Physical length (bp) | Genetic Length (cM) | α | β | Mean TMRCA (generations) |
|---|---|---|---|---|---|---|---|---|
| S_Mandenka-2A + S_Khomani_San-1B | Concordant | SGDP | 136,494,791 – 136,602,042 |
107,250.5 |
0.01678074 |
22 | 52.4802 | 8,384.1 |
| S_Mandenka-2B + S_Khomani_San-1A | Concordant | SGDP | 136,556,012 – 136,565,535 |
9,523.0 |
0.00304087 |
1 | 5.5710 | 3,590.0 |
| S_Ju_hoan_North-1B + S_Khomani_San-1B | Concordant | SGDP | 135,436,058 – 136,772,749 |
1,336,691.0 |
0.36529398 |
176 | 642.6117 | 5,477.6 |
| S_Ju_hoan_North-1B + S_Mandenka-2A | Concordant | SGDP | 136,494,791 – 136,602,042 |
107,250.5 |
0.01678074 |
21 | 52.4802 | 8,003.0 |
| S_BantuTswana-2B + S_Khomani_San-1A | Concordant | SGDP | 136,555,141 – 136,566,474 |
11,333.0 |
0.00454331 |
1 | 6.4398 | 3,105.7 |
| S_Mandenka-2B + S_Khomani_San-1B | Concordant | SGDP | 136,556,012 – 136,565,535 |
9,523.0 |
0.00304087 |
1 | 5.5710 | 3,590.0 |
| S_BantuTswana-2B + S_Mandenka-2B | Concordant | SGDP | 136,556,012 – 136,646,325 |
90,312.5 |
0.01676442 |
22 | 44.3500 | 9,921.1 |
| S_BantuTswana-2B + S_Ju_hoan_North-1B | Concordant | SGDP | 136,555,141 – 136,632,444 |
77,302.5 |
0.01599323 |
15 | 38.1052 | 7,872.9 |
| S_Khomani_San-1B + S_Saami-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Greek-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Punjabi-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Estonian-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2A + S_Dusun-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Dai-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Saharawi-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + B_Ju_hoan_North-4A | Discordant | SGDP | 135,437,187 – 136,572,640 |
1,135,453.0 |
0.33627945 |
271 | 546.0174 | 9,926.4 |
| S_Khomani_San-1A + S_Ju_hoan_North-2B | Discordant | SGDP | 136,411,978 – 136,787,291 |
375,313.0 |
0.07797775 |
31 | 181.1502 | 3,422.6 |
| S_Khomani_San-1A + S_Turkish-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2A + S_Dinka-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2A + S_Yoruba-1B | Discordant | SGDP | 136,556,012 – 136,564,602 |
8,590.0 |
0.00300843 |
2 | 5.1232 | 7,807.6 |
| S_Mandenka-2A + S_Czech-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Norwegian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Tlingit-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Turkish-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Miao-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Uygur-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2A + S_Naxi-1A | Discordant | SGDP | 135,760,098 – 136,564,602 |
804,504.5 |
0.06697593 |
86 | 387.1622 | 4,442.6 |
| S_Khomani_San-1A + S_Spanish-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Dai-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Yemenite_Jew-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Kinh-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Piapoco-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Kusunda-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Cambodian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Burusho-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Xibo-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Luhya-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Kinh-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Bulgarian-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Atayal-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Lezgin-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Finnish-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Mandenka-2B + S_Mende-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Basque-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Mozabite-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Druze-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Mixe-3A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_North_Ossetian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Mongola-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + B_Crete-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Mongola-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Pima-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Tubalar-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Adygei-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Naxi-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Adygei-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Miao-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Tajik-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Hezhen-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Turkish-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Thai-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + B_Sardinian-3B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Chukchi-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Karitiana-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Mozabite-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Mixtec-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Mansi-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Aleut-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Brahmin-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Dai-3B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Hazara-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Daur-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Punjabi-4B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Yi-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Czech-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Xibo-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_English-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Sindhi-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_English-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Bulgarian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_BantuKenya-1A | Discordant | SGDP | 136,556,012 – 136,564,602 |
8,590.0 |
0.00300843 |
3 | 5.1232 | 11,711.4 |
| S_Khomani_San-1B + S_English-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Estonian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Estonian-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Finnish-3A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Finnish-3B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Saami-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_French-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_French-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Georgian-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Basque-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Icelandic-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Icelandic-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Kyrgyz-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Iranian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Ju_hoan_North-3B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Samaritan-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Ju_hoan_North-1A | Discordant | SGDP | 136,559,711 – 136,572,640 |
12,929.0 |
0.00056393 |
3 | 7.2059 | 8,326.5 |
| S_Khomani_San-1A + S_Tuscan-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Yemenite_Jew-2B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Jordanian-3B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + B_French-3B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Norwegian-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Piapoco-1B | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Orcadian-1A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1B + S_Pima-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
| S_Khomani_San-1A + S_Orcadian-2A | Discordant | SGDP | 136,564,590 – 136,564,602 |
12.5 |
0.00000044 |
2 | 1.0060 | 39,761.4 |
Data shown in this table can be downloaded from this page.
| α | Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| β | Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| Mean TMRCA | Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default. |
|---|
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