Genealogical Estimation of Variant Age (GEVA)
Inference of the ancestral origin of a genetic variant at a single locus
rs373477291
Alleles:
reference
Aancestral
alternate
Gderived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome 
Explore
10
position 31,768,854 (GRCh37)
Explore rs373477291 on Ensembl!
Allele frequency in SGDP ⇪
| Sample | 99.5% |
0.5% |
|
AFR |
96.6% |
3.4% |
|
AMR |
100.0% |
0.0% |
|
CAS |
100.0% |
0.0% |
|
EAS |
100.0% |
0.0% |
|
OCN |
100.0% |
0.0% |
|
SAS |
100.0% |
0.0% |
|
WEA |
100.0% |
0.0% |
|
| reference | ← allele frequency → | alternate |
Select clock model
Age estimation summary
| Data source | Estimated age of G allele |
# pairs = concordant + discordant | Quality score |
|---|---|---|---|
| Genomes in SGDP | 4,933.3 generations | 100 = 3 + 97 | 0.667 |
Pairwise results table
| Haplotype pair | Pair type | Data source | Breakpoint positions | Physical length (bp) | Genetic Length (cM) | α | β | Mean TMRCA (generations) |
|---|---|---|---|---|---|---|---|---|
| S_Mbuti-3B + S_Mbuti-2B | Concordant | SGDP | 31,478,977 – 31,827,533 |
348,556.5 |
0.11248423 |
3 | 90.9874 | 659.4 |
| S_Biaka-2A + S_Mbuti-2B | Concordant | SGDP | 31,645,663 – 31,820,336 |
174,673.5 |
0.00539778 |
3 | 5.3182 | 11,282.0 |
| S_Biaka-2A + S_Mbuti-3B | Concordant | SGDP | 31,557,284 – 31,820,336 |
263,052.0 |
0.01107474 |
3 | 9.8598 | 6,085.3 |
| S_Mbuti-2B + S_Maori-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Mala-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Tubalar-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Thai-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Iraqi_Jew-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Chane-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-5A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Estonian-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Bougainville-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-3B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Maori-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_BantuTswana-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Madiga-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-4A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Abkhasian-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-4B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Saami-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Tu-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Jordanian-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Uygur-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-14A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Mozabite-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Yi-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-7B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Korean-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-9A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Kinh-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-12B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Chukchi-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Papuan-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Brahmin-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Mansi-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Kalash-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Kalash-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Czech-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Burusho-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Finnish-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Estonian-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Icelandic-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Finnish-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Palestinian-1A | Discordant | SGDP | 31,715,606 – 31,768,868 |
53,262.0 |
0.00171967 |
3 | 2.3757 | 25,255.3 |
| S_Biaka-2A + S_French-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Yemenite_Jew-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_French-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Piapoco-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Hungarian-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Han-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Icelandic-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Uygur-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Bergamo-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Mbuti-3A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Sardinian-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_She-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Tuscan-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Burmese-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Orcadian-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Mbuti-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Polish-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Dusun-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Russian-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Papuan-14B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + S_Saharawi-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Itelman-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + B_Papuan-15B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Mala-3A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Biaka-2A + B_Dinka-3B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Madiga-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-3B + S_Yakut-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Pathan-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-3B + S_Lahu-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Luhya-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-3B + S_Tu-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Bulgarian-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-3B + S_Mbuti-2A | Discordant | SGDP | 31,557,284 – 31,768,868 |
211,583.5 |
0.00894823 |
3 | 8.1586 | 7,354.2 |
| S_Mbuti-2B + S_English-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-3B + S_Japanese-3B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Finnish-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Mixe-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Saami-1A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Quechua-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_French-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Tubalar-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Iranian-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Altaian-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Iraqi_Jew-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Ulchi-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Bergamo-2B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Ulchi-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Orcadian-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Even-3B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + B_French-3B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Yakut-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Karitiana-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Naxi-3A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Pima-2A | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
| S_Mbuti-2B + S_Miao-1B | Discordant | SGDP | 31,768,849 – 31,768,868 |
19.0 |
0.00000000 |
3 | 1.0000 | 60,000.0 |
Data shown in this table can be downloaded from this page.
| α | Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| β | Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| Mean TMRCA | Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default. |
|---|
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