Genealogical Estimation of Variant Age (GEVA)
Inference of the ancestral origin of a genetic variant at a single locus
rs574660834
Alleles:
reference
Gancestral
alternate
Aderived
Age estimated for the alternate allele, assuming that it was derived from the reference allele as the ancestral state.
How was the ancestral/derived state determined?Chromosome
Explore
2
position 136,572,212 (GRCh37)
Explore rs574660834 on Ensembl!
Allele frequency in SGDP ⇪
| Sample | 99.6% |
0.4% |
|
AFR |
97.7% |
2.3% |
|
AMR |
100.0% |
0.0% |
|
CAS |
100.0% |
0.0% |
|
EAS |
100.0% |
0.0% |
|
OCN |
100.0% |
0.0% |
|
SAS |
100.0% |
0.0% |
|
WEA |
100.0% |
0.0% |
|
| reference | ← allele frequency → | alternate |
Select clock model
Age estimation summary
| Data source | Estimated age of A allele |
# pairs = concordant + discordant | Quality score |
|---|---|---|---|
| Genomes in SGDP | 1,816.8 generations | 95 = 1 + 94 | 0.989 |
Pairwise results table
| Haplotype pair | Pair type | Data source | Breakpoint positions | Physical length (bp) | Genetic Length (cM) | α | β | Mean TMRCA (generations) |
|---|---|---|---|---|---|---|---|---|
| S_Ju_hoan_North-3B + S_Ju_hoan_North-2B | Concordant | SGDP | 135,141,319 – 136,574,082 |
1,432,763.0 |
0.80129880 |
50 | 688.7262 | 1,452.0 |
| S_Ju_hoan_North-2B + S_Atayal-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Sindhi-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Chukchi-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Mixe-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Yemenite_Jew-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Kyrgyz-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_French-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Eskimo_Chaplin-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Even-2A | Discordant | SGDP | 136,556,402 – 136,739,216 |
182,814.0 |
0.02242194 |
18 | 88.7507 | 4,056.3 |
| S_Ju_hoan_North-3B + S_Eskimo_Sireniki-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Aleut-1B | Discordant | SGDP | 136,549,528 – 136,762,052 |
212,524.0 |
0.02737236 |
24 | 103.0115 | 4,659.7 |
| S_Ju_hoan_North-3B + S_Ulchi-1A | Discordant | SGDP | 136,549,528 – 136,762,052 |
212,524.0 |
0.02737236 |
21 | 103.0115 | 4,077.2 |
| S_Ju_hoan_North-3B + S_BantuHerero-1B | Discordant | SGDP | 136,493,766 – 136,762,052 |
268,286.0 |
0.03370694 |
28 | 129.7773 | 4,315.1 |
| S_Ju_hoan_North-2B + S_Estonian-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Finnish-3A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Even-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Icelandic-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Oroqen-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_North_Ossetian-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Oroqen-2A | Discordant | SGDP | 136,493,766 – 136,739,216 |
245,450.0 |
0.03252613 |
27 | 118.8160 | 4,544.8 |
| S_Ju_hoan_North-2B + B_Ju_hoan_North-4B | Discordant | SGDP | 136,572,208 – 136,976,283 |
404,075.5 |
0.25208214 |
87 | 194.9562 | 8,925.1 |
| S_Ju_hoan_North-3B + S_Uygur-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Xibo-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Itelman-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Burusho-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Eskimo_Naukan-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Punjabi-4A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Eskimo_Sireniki-2A | Discordant | SGDP | 135,759,069 – 136,762,052 |
1,002,983.0 |
0.09320676 |
114 | 482.4318 | 4,726.1 |
| S_Ju_hoan_North-2B + S_English-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Irula-1B | Discordant | SGDP | 136,559,711 – 136,762,052 |
202,341.0 |
0.02182570 |
26 | 98.1237 | 5,299.4 |
| S_Ju_hoan_North-2B + S_Estonian-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Somali-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_BantuKenya-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Pathan-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Georgian-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Burusho-1B | Discordant | SGDP | 135,759,069 – 136,762,052 |
1,002,983.0 |
0.09320676 |
117 | 482.4318 | 4,850.4 |
| S_Ju_hoan_North-2B + S_Druze-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Punjabi-3B | Discordant | SGDP | 136,493,766 – 136,739,216 |
245,450.0 |
0.03252613 |
26 | 118.8160 | 4,376.5 |
| S_Ju_hoan_North-2B + S_Orcadian-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Abkhasian-1B | Discordant | SGDP | 136,555,141 – 136,762,052 |
206,910.5 |
0.02601890 |
22 | 100.3170 | 4,386.1 |
| S_Ju_hoan_North-2B + S_Adygei-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Albanian-1A | Discordant | SGDP | 135,759,069 – 136,762,052 |
1,002,983.0 |
0.09320676 |
110 | 482.4318 | 4,560.2 |
| S_Ju_hoan_North-2B + B_Crete-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Bulgarian-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Karitiana-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Bulgarian-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Dai-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Estonian-2A | Discordant | SGDP | 136,473,791 – 136,677,400 |
203,609.0 |
0.03495840 |
21 | 98.7323 | 4,253.9 |
| S_Ju_hoan_North-2B + S_Kinh-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Saami-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Brahmin-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Hungarian-2B | Discordant | SGDP | 136,555,141 – 136,739,216 |
184,074.5 |
0.02483808 |
21 | 89.3558 | 4,700.3 |
| S_Ju_hoan_North-2B + S_Hazara-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Palestinian-1B | Discordant | SGDP | 136,555,141 – 136,654,786 |
99,644.5 |
0.02265865 |
10 | 48.8294 | 4,095.9 |
| S_Ju_hoan_North-2B + S_Punjabi-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Sardinian-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Bulgarian-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Tuscan-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Czech-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Jordanian-3B | Discordant | SGDP | 136,549,528 – 136,762,052 |
212,524.0 |
0.02737236 |
22 | 103.0115 | 4,271.4 |
| S_Ju_hoan_North-2B + S_English-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Orcadian-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Estonian-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Ju_hoan_North-2A | Discordant | SGDP | 136,411,978 – 137,134,525 |
722,547.0 |
0.65104046 |
23 | 347.8226 | 1,322.5 |
| S_Ju_hoan_North-2B + S_Finnish-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Spanish-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Finnish-3B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Tajik-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Saami-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + B_Papuan-15B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Basque-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + B_Sardinian-3B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Icelandic-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + B_Karitiana-3A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Iranian-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-3B + S_Chane-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Tuscan-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Mozabite-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Norwegian-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Mongola-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Orcadian-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Tlingit-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Adygei-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Aleut-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Turkish-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Miao-1A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Yemenite_Jew-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Uygur-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Ju_hoan_North-1B | Discordant | SGDP | 136,555,141 – 136,572,288 |
17,147.0 |
0.00474486 |
6 | 9.2306 | 13,000.3 |
| S_Ju_hoan_North-2B + S_Xibo-1B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Saharawi-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Yi-2B | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Piapoco-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
| S_Ju_hoan_North-2B + S_Mozabite-2A | Discordant | SGDP | 136,572,208 – 136,572,288 |
80.5 |
0.00000281 |
2 | 1.0386 | 38,511.9 |
Data shown in this table can be downloaded from this page.
| α | Shape parameter of the Gamma distribution, calculated from the number of pairwise differences along the sequence of the inferred shared haplotype segment (mutation clock), or the breakpoints detected (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| β | Rate parameter of the Gamma distribution, calculated from the physical length of the inferred shared haplotype segment and the mutation rate (mutation clock), or the genetic length given the variable recombination rate (recombination clock), or both (joint clock); plus the parameter of the coalescent prior distribution (equal to 1 by default). |
| Mean TMRCA | Calculated as the mean of the Gamma distribution with parameters α and β, multiplied by 2 x Ne, where Ne = 10,000 by default. |
|---|
Patrick K. Albers